Valverde has also made four changes to his side that beat Leganes with ease at the weekend. Umtiti, Alba, Busquets and Iniesta start this evening in a 4-4-2 formation.
Roma have made four changes from their defeat against Fiorentina last week. Florenzi, De Rossi, Kolarov and Schick come into the fold this evening, with Eusebio expected to line up in a 3-5-2 formation. Schick and Dzeko will lead the line.
Barcelona subs: Denis Suarez, Ousmane Dembele, Jasper Cillessen, Paulinho, Paco Alcacer, Andre Gomes, Thomas Vermaelen.
BARCELONA (4-4-2): Marc-Andre ter Stegen; Nelson Semedo, Gerard Pique, Samuel Umtiti, Jordi Alba; Sergi Roberto, Ivan Rakitic, Sergio Busquets, Andres Iniesta; Lionel Messi, Luis Suarez.
Roma subs: Lorenzo Pellegrini, Cengiz Under, Maxime Gonalons, Bruno Peres, Lukasz Skorupski, Gerson, Stephan El Shaarawy.
ROMA (3-5-2): Alisson; Kostas Manolas, Federico Fazio, Juan Jesus; Alessandro Florenzi, Radja Nainggolan, Daniele De Rossi, Kevin Strootman, Aleksandar Kolarov; Patrik Schick, Edin Dzeko.