With one – if not both – eyes on Thursday’s Europa League semi-final second leg in Madrid, Wenger has named a very experimental side, making seven changes from last weekend’s 4-1 win over West Ham. January signing and 20-year-old centre-half Mavropanos is handed a surprise Premier League debut, while Chambers, Kolasinac, Maitland-Niles, Nelson and Aubameyang are also called into the XI along with Mkhitaryan, who makes his return following a lengthy injury absence.
Jose Mourinho names a full-strength side as he looks to continue his dominance over Wenger, making just one change from last weekend’s FA Cup victory over Tottenham – Lindelof replacing Phil Jones in the centre of defence.
SUBS: Rob Holding, Nacho Monreal, Danny Welbeck, Petr Cech, Edward Nketiah, Jordi Osei-Tutu, Joe Willock.
ARSENAL (4-2-3-1): David Ospina; Hector Bellerin, Konstantinos Mavropanos, Calum Chambers, Sead Kolasinac; Ashley Maitland-Niles, Granit Xhaka; Henrikh Mkhitaryan, Reiss Nelson, Alex Iwobi; Pierre-Emerick Aubameyang.
SUBS: Marcos Rojo, Juan Mata, Anthony Martial, Marcus Rashford, Marouane Fellaini, Scott McTominay, Joel Castro.
MANCHESTER UNITED (4-3-3): David de Gea; Antonio Valencia, Victor Lindelof, Chris Smalling, Ashley Young; Ander Herrera, Nemanja Matic, Paul Pogba; Jesse Lingard, Alexis Sanchez, Romelu Lukaku.